Tfelt-Hansen P [Triptans versus other migraine medicine - secondary publication] [English Abstract, Journal Article] Ugeskr Laeger 2009 Apr 27; 171(18):1485-7.
The introduction of triptans in the treatment of migraine was apparently a revolution.Comparative randomised trials do not, however, show a clearcut picture.Oral triptans outperform oral ergotamine most because of the extremely low (< 1%) oral bioavailability of ergotamine. Compared with NSAIDs, triptants are not, in most cases, superior to aspirin. Aspirin is suggested as first-choice drug in migraine treatment. An additional advantage of aspirin is that is it much less expensive than triptans.
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